Réponse Signature

Universal Cellular Regeneration Collection

At the heart of MATIS Paris lies Réponse Signature, our iconic cellular regeneration collection designed to protect, strengthen and preserve youthful-looking skin.

Combining the exclusive Cell-Skin, Cell-Expert and Cell-Essence trio, each formula works to reinforce the skin’s natural defence system, improve resilience and reveal a smoother, firmer and more radiant complexion.

Shop the Collection

Cellular longevity.
Protected by science.

Réponse Signature is MATIS Paris’ iconic cellular regeneration collection, designed to protect the skin’s youth capital and preserve its natural ability to renew. Powered by white rose stem cell technology and advanced protective actives, each formula helps strengthen the skin’s environment, improve resilience and reveal a smoother, firmer and more radiant complexion.

Experience Réponse Signature
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White Rose
Stem Cells

Helps preserve the skin’s cellular environment.

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Protective
Ring System

Supports defence against daily aggressions.

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Cellular
Oxygenation

Boosts vitality and helps revive dull-looking skin.

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Youth Capital
Protection

Protects, strengthens and preserves youthful-looking skin.

The Science Behind Réponse Signature

White Rose Stem Cell Technology supporting cellular longevity and youthful-looking skin.

WHITE ROSE STEM CELL TECHNOLOGY

Exclusive white rose stem cell technology helps preserve the skin's youthful capital while supporting natural cellular renewal and resilience.

Advanced Cellular Regeneration Technology supporting skin renewal.

ADVANCED CELLULAR REGENERATION

Inspired by advanced skin cell science, this technology helps reinforce natural regeneration for smoother, firmer-looking skin.

Biomimetic Peptide Complex reinforcing skin resilience.

BIOMIMETIC PEPTIDE
COMPLEX

Advanced biomimetic peptides help strengthen the skin barrier, improve resilience and support daily environmental protection.

Cell-Skin Protective Complex preserving skin integrity.

CELL-SKIN PROTECTIVE COMPLEX

An intelligent protective complex designed to reinforce the skin's defence system and maintain youthful vitality.

Cellular Longevity Technology supporting skin renewal and protection.

CELLULAR LONGEVITY TECHNOLOGY

Inspired by longevity science, this technology helps preserve skin vitality and reveal a smoother, firmer and more radiant complexion.

Who is Réponse Signature for?

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All skin types seeking cellular longevity care
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First signs of ageing, dullness or fatigue
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Skin exposed to stress, pollution and daily aggressors
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Loss of radiance, resilience and smoothness
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Anyone wanting to preserve youthful-looking skin
Model applying MATIS Réponse Signature Cell-Eyes eye contour treatment

The Complete Réponse Signature Collection

A universal cellular regeneration ritual designed to protect, strengthen and preserve the skin’s youthful-looking vitality day after day.

MATIS Réponse Signature Cell Essence

Cell Essence

Pre-care essence

MATIS Réponse Signature Cell-Eyes

Cell-Eyes

Eye contour care

MATIS Réponse Signature Cell Expert Serum

Cell Expert

Universal serum

MATIS Réponse Signature Cell Rejuvenate 28-day treatment

Cell Rejuvenate

28-day treatment

MATIS Réponse Signature Cell Skin Cream

Cell Skin

Universal cream

Use Cell Essence, Cell-Eyes, Cell Expert and Cell Skin daily. Complete the ritual with Cell Rejuvenate as an intensive 28-day boost every 3 to 6 months.

Frequently Asked Questions

Everything you need to know about the MATIS Réponse Signature cellular longevity collection.

Réponse Signature is MATIS Paris' iconic cellular longevity collection, created to protect, strengthen and preserve youthful-looking skin. It helps reinforce the skin's natural defence system while supporting long-term resilience, firmness and radiance.
Réponse Signature is suitable from the first visible signs of ageing and is also ideal as a preventive skincare routine for anyone wishing to preserve healthy, youthful-looking skin.
Rather than focusing only on correcting visible wrinkles, Réponse Signature supports cellular longevity by helping protect the skin's natural renewal processes and strengthening its ability to resist everyday environmental stress.
Use Cell Essence, Cell-Eyes, Cell Expert Serum and Cell Skin Cream daily. Complete the ritual with Cell Rejuvenate as an intensive 28-day treatment every 3 to 6 months to boost skin vitality and resilience.
Yes. The collection is formulated to respect skin comfort while supporting long-term skin health. Cell-Eyes is fragrance-free and ophthalmologically tested for the delicate eye area.
Absolutely. Réponse Signature creates an excellent foundation for healthy skin and can be combined with targeted MATIS collections such as Réponse Corrective, Réponse Preventive, Réponse Caviar or Réponse Densité according to your skin's changing needs.

Discover the Réponse Signature Collection

Explore the five essential treatments of MATIS Réponse Signature, created to protect, strengthen and preserve youthful-looking skin through advanced cellular longevity science.

MATIS Réponse Signature Cell Essence

Cell Essence

Pre-care essence to prepare, hydrate and energise the skin.

 MATIS Réponse Signature Cell-Eyes

Cell-Eyes

Advanced eye contour care for puffiness, dark circles and fatigue.

 MATIS Réponse Signature Cell Expert Serum

Cell Expert

Universal serum for cellular regeneration, vitality and resilience.

 MATIS Réponse Signature Cell Rejuvenate

Cell Rejuvenate

Intensive 28-day treatment to boost renewal and radiance.

 MATIS Réponse Signature Cell Skin Cream

Cell Skin

Universal cream to protect, nourish and preserve skin longevity.
SHOP THE COMPLETE RÉPONSE SIGNATURE COLLECTION